pickdown with a disease down with a disease {adj. phr.} Ill or sick. Aunt Liz is down with the flu this week; she has to stay in bed. Categories: add yours adjective Source: A Dictionary of American Idioms 'down with a disease' on video Phish Down With Disease Music Video (1994) Phish - 8/31/2019 - Down With Disease (4K HDR) "Down With Disease" - Star Lake 98 DVD Phish - 8/07/2018 - "Down with Disease" sort: relevance, mode: exact match, q: "down with a disease", maxResults: 4, videoEmbeddable: true, videoSyndicated: true, safeSearch: strict, type: video Subscribe to: American IdiomsEnglish Slang Leave my opinion