pickheads-up . heads-up {adj.}, {informal} Wide-awake; alert; watchful; intelligent. You must play hard, heads-up baseball to win this game. Compare: ON ONE'S TOES, ON THE BALL. Categories: add yours adjective informal Source: A Dictionary of American Idioms 'heads-up' on video Heads up || SS8inJapan ๐ TRFN - HEADS UP (Original Mix) Ellen and Owen Wilson Play 'Heads Up!' Ellen and Drew Barrymore's Giant, Royal Game of 'Heads Up!' sort: relevance, mode: exact match, q: "heads-up", maxResults: 4, videoEmbeddable: true, videoSyndicated: true, safeSearch: strict, type: video Subscribe to: American IdiomsEnglish Slang Discuss